The 2020-21 Total CAF Confederation Cup Group Stage draw was conducted today Monday 22 February 2021 in Cairo, Egypt. It was conducted by head of Competitions, Khaled Nassar. Meanwhile, the first leg of the additional second preliminary round took place on February 13 and 14. It was disclosed on the official website of CAF that the aggregate winners from the last leg of preliminaries will qualify for the group stages. The matches are scheduled for March 10, 17, April 4, 11, 21, 28.
Group A: Enyimba (NGR), Entente Setif (ALG), Orlando Pirates (RSA), Al Ahly Benghazi (LBA)
Group B: Renaissance Berkane (MAR, holders), JS Kabylie (ALG), Coton Sport (CMR), NAPSA Stars (ZAM)
Group C: Etoile Sahel (TUN) or Young Buffaloes (ESW), CS Sfaxien (TUN), Salitas (BUR), ASC Jaraaf (SEN)
Group D: Raja Casablanca (MAR), Pyramids (EGY), Nkana (ZAM), Namungo (TAN) or Primeiro Agosto (ANG)